NALT

Preferred term

lymphocyte function-associated antigen-1

Chemical

An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A antigen comprises the alpha chain and the CD18 antigen (antigen, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-cells; B-cells; and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.

integrin alphaLbeta2
leukocyte function associated antigen-1
LFA-1 (lymphocyte function-associated antigen-1)

Field 001 in MARC Authority Format

69241

Spanish

antígeno-1 asociado a la función del linfocito

URI

https://lod.nal.usda.gov/nalt/211305

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Created 2/28/14, last modified 6/28/17