NALT

Preferred term

low density lipoprotein receptors

Chemical

Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.

lipoprotein receptors

LDL (low density lipoprotein) receptors
LDL receptors
lipoprotein LDL receptors

Field 001 in MARC Authority Format

88470

Spanish

receptores de lipoproteínas de baja densidad

URI

https://lod.nal.usda.gov/nalt/322237

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Created 7/11/18, last modified 11/14/18