NALT

Preferred term

quantitative structure-activity relationships

Topic

A mathematical relationship between a quantifiable aspect of chemical structure and a chemical property or reactivity or a well defined biological activity, such as toxicity. Using a sample set of chemicals, a relationship is established between one or many physical-chemical properties a chemical possesses due to its structure and a chemical property or biological activity of concern. This mathematical expression is then used to predict the chemical property or biological response expected from other chemicals with similar structures. It is based on the presumption that similar molecules or chemical structures have similar properties or biological activities or toxicity potential.

quantitative structure-toxicity relationships

in vitro to in vivo extrapolation

QSAR (quantitative structure-activity relationships)
QSPR (quantitative structure property relationship)
quantitative structure activity relationships
quantitative structure property relationship
quantitative structure-property relationships

Field 001 in MARC Authority Format

31233

Spanish

relaciones cuantitativas de actividad estructural

URI

https://lod.nal.usda.gov/nalt/60701

Download this concept

Created 1/19/06, last modified 2/26/20