@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:21100_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "A class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms."@en, "Tipo de medicamentos que actúan por inhibición selectiva del flujo de calcio entrante a través de las membranas celulares o en la liberación y unión de calcio en depósitos intracelulares. Puesto que inducen la relajación vascular y de la musculatura lisa, se utilizan en la terapia medicamentosa de la hipertensión y de los espasmos cerebrovasculares como agentes protectores del miocardio, y en la relajación de espasmos uterinos."@es ;
  dc:source "Medical Subject Headings 2012" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:21100
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  dc:created "2006-01-19"^^xsd:date ;
  dc:modified "2016-08-26"^^xsd:date ;
  skos:broader nalt:10385 ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh85018769> ;
  skos:definition nalt:21100_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:narrower nalt:21101 ;
  skos:prefLabel "bloqueadores de los canales de calcio"@es, "calcium channel blockers"@en ;
  skos:related nalt:21102, nalt:286434, nalt:264312 ;
  ns0:marc001 "6382" .

nalt:21101
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:21100 ;
  skos:prefLabel "verapamil"@es, "verapamil"@en .

nalt:21102
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "canales de calcio"@es, "calcium channels"@en ;
  skos:related nalt:21100 .

nalt:286434
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "conotoxins"@en, "conotoxinas"@es ;
  skos:related nalt:21100 .

nalt:10385
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:21100 ;
  skos:prefLabel "agentes cardiovasculares"@es, "cardiovascular agents"@en .

nalt:264312
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "ruthenium red"@en, "rojo de rutenio"@es ;
  skos:related nalt:21100 .

