@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:222853_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Receptor de superficie celular que interviene en la regulación del crecimiento y la diferenciación celular. Es específico para el factor de crecimiento epidérmico y los péptidos relacionados con este, incluidos el factor de crecimiento transformador alfa, la anfirregulina y el factor de crecimiento similar al factor de crecimiento epidérmico de unión a heparina. La unión del ligando al receptor estimula su actividad intrínseca de tirosina quinasa y la rápida internalización del complejo receptor-ligando en la célula."@es, "A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for epidermal growth factor and EGF related peptides including transforming growth factor alpha, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell."@en ;
  dc:source "Medical Subject Headings 2014" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:222853
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  dc:created "2014-07-25"^^xsd:date ;
  dc:modified "2014-11-17"^^xsd:date ;
  skos:altLabel "epidermal growth factor receptor protein-tyrosine kinase"@en, "epidermal growth factor-urogastrone receptor"@en, "transforming growth factor-alpha receptor"@en, "urogastrone receptor"@en, "EGF receptor"@en, "erbB-1 proto-oncogene protein"@en, "transforming-growth factor alpha receptor"@en, "c-erbB-1 protein"@en, "transforming growth factor alpha receptor"@en, "TGF-alpha receptor"@en, "epidermal growth factor receptor kinase"@en, "EGFR protein"@en ;
  skos:broader nalt:223390, nalt:223335, nalt:146200 ;
  skos:definition nalt:222853_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "receptores del factor de crecimiento epidérmico"@es, "epidermal growth factor receptors"@en ;
  skos:related nalt:37571 ;
  ns0:marc001 "66476" .

nalt:146200
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:222853 ;
  skos:prefLabel "receptor de la proteína-tirosina quinasa"@es, "receptor protein-tyrosine kinase"@en .

nalt:223335
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:222853 ;
  skos:prefLabel "peptide receptors"@en, "receptores de péptidos"@es .

nalt:37571
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "factor de crecimiento epidérmico"@es, "epidermal growth factor"@en ;
  skos:related nalt:222853 .

nalt:223390
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:222853 ;
  skos:prefLabel "gastrointestinal hormone receptors"@en, "receptores de la hormona gastrointestinal"@es .