@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:222856_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (epidermal growth factor receptor), the erbB-3 receptor and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members."@en, "Receptor de la proteína tirosina quinasa de la superficie celular sobreexpresado en un número significativo de adenocarcinomas. Presenta una gran homología y puede heterodimerizar con el receptor de factor de crecimiento epidérmico y los receptores erbB-3 y erbB-4. La activación del receptor erbB-2 tiene lugar durante la formación del heterodímero con miembros de la familia de un receptor erbB unido al ligando."@es ;
  dc:source "Medical Subject Headings 2014" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:222856
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  dc:created "2014-07-25"^^xsd:date ;
  dc:modified "2015-12-10"^^xsd:date ;
  skos:altLabel "erbB-2 proto-oncogene protein"@en, "proto-oncogene protein HER-2"@en, "human epidermal growth factor receptor-2"@en, "neu receptor"@en, "c-erbB-2 protein"@en, "proto-oncogene proteins c-erbB-2"@en, "erbB-2 receptor protein-tyrosine kinase"@en, "HER-2 proto-oncogene protein"@en, "proto-oncogene protein c-neu"@en, "c-erbB2 receptor"@en, "c-neu proto-oncogene protein"@en ;
  skos:broader nalt:146200 ;
  skos:definition nalt:222856_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "erbB-2 receptor"@en, "receptor erbB-2"@es ;
  ns0:marc001 "66506" .

nalt:146200
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:222856 ;
  skos:prefLabel "receptor de la proteína-tirosina quinasa"@es, "receptor protein-tyrosine kinase"@en .