@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:243409_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Chemokine (C-C Motif) Receptor 1, encoded by the CCR1 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells (monocytes, macrophages, neutrophils and eosinophils) to the site of inflammation. This gene may have roles in host protection from inflammatory response, and susceptibility to virus and parasite."@en, "Receptor 1 de quimiocina C-C, codificado por el gen CCR1. Es un miembro de la familia de receptores de quimiocina beta y una proteína transmembranal de siete hélices, similar a los receptores acoplados a proteínas G. Entre los ligandos de este receptor se incluyen la proteína inflamatoria de macrófagos 1 alfa (MIP-1 alfa), la proteína expresada y secretada por células T normales reguladas tras la activación (RANTES), la proteína 3 quimioatrayente de monocitos (MCP-3) y el factor 1 inhibidor del progenitor mieloide (MPIF-1). La transducción de señales mediada de las quimiocinas y sus receptores resulta esencial para atraer células efectoras inmunitarias (monocitos, macrófagos, neutrófilos y eosinófilos) al lugar de la inflamación. Este gen puede realizar funciones en la protección del huésped de una respuesta inflamatoria y en la susceptibilidad a virus y parásitos."@es ;
  dc:source "National Cancer Institute Thesaurus" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:243409
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  dc:created "2015-03-10"^^xsd:date ;
  dc:modified "2015-11-16"^^xsd:date ;
  skos:altLabel "LD78 cytokine receptor"@en, "chemokine (C-C motif) receptor 1"@en, "C-C chemokine receptor type 1"@en, "C-C CKR1 receptor"@en, "macrophage inflammatory protein 1alpha receptor"@en, "RANTES receptor"@en, "CD191 antigen"@en ;
  skos:broader nalt:243407 ;
  skos:definition nalt:243409_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "CCR1 receptor"@en, "receptor CCR1"@es ;
  skos:related nalt:236773, nalt:228804, nalt:236678 ;
  ns0:marc001 "64628" .

nalt:236773
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "chemokine CCL7"@en, "quimiocina CCL7"@es ;
  skos:related nalt:243409 .

nalt:228804
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "chemokine CCL3"@en, "quimiocina CCL3"@es ;
  skos:related nalt:243409 .

nalt:236678
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "chemokine CCL5"@en, "quimiocina CCL5"@es ;
  skos:related nalt:243409 .

nalt:243407
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:243409 ;
  skos:prefLabel "chemokine receptors"@en, "receptores de quimiocinas"@es .