@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:271059_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Amplio grupo de canales catiónicos con seis dominios transmembranales que se hallan en los organismos eucariontes eucariotas. Dado que la función que desempeñan en la percepción sensorial es diversa, se clasifican de acuerdo con la homología de sus secuencias. Presentan sensibilidades iónica y al voltaje reducidas. Deben su nombre a un mutante del género Drosophila que presentaba potenciales de receptor transitorios en respuesta a la luz. Los subgrupos TRPC, TRPV y TRPM comparten un motivo de 25 aminoácidos en el que se encuentra una caja TRP (EWKFAR), en la región carboxiterminal (C-terminal) próxima al sexto segmento transmembranal (S6). Los subgrupos TRPC, TRPV y TRPN presentan repeticiones idénticas a las de la anquirina. Algunos están asociados funcionalmente a la tirosina quinasa o a las fosfolipasas tipo C."@es, "A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with sensation is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a Drosophila mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. Ankyrin repeats are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with tyrosine kinase or type C phospholipases."@en ;
  dc:source "Medical Subject Headings 2016" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:271059
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  dc:created "2016-01-27"^^xsd:date ;
  dc:modified "2018-10-03"^^xsd:date ;
  skos:altLabel "TRP membrane proteins"@en, "TRP cation channels"@en, "transient receptor potential (TRP) channels"@en ;
  skos:broader nalt:21103 ;
  skos:definition nalt:271059_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:narrower nalt:324959 ;
  skos:prefLabel "canales receptores transitorios de potencial"@es, "transient receptor potential channels"@en ;
  skos:related nalt:47612, nalt:23427, nalt:23048 ;
  ns0:marc001 "79409" .

nalt:324959
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:271059 ;
  skos:prefLabel "transient receptor potential vanilloid channels"@en, "receptores de potencial transitorio vaniloide"@es .

nalt:21103
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:271059 ;
  skos:prefLabel "canales iónicos"@es, "ion channels"@en .

nalt:23048
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "cationes"@es, "cations"@en ;
  skos:related nalt:271059 .

nalt:23427
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "permeabilidad de la membrana"@es, "membrane permeability"@en ;
  skos:related nalt:271059 .

nalt:47612
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "transporte de iones"@es, "ion transport"@en ;
  skos:related nalt:271059 .