@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .

<https://lod.nal.usda.gov/naltv#Definition>
  a owl:Class ;
  rdfs:label "Concept definition"@en .

nalt:28890315_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "This test is an alternative to the Median Lethal Dose (LD50) test in which animals are used for acute toxicity testing. Animals are dosed one at a time with a drug or toxic substance. If an animal survives, the dose for the next animal is increased; if it dies, the dose is decreased to determine toxicity level."@en, "Prueba alternativa a la prueba de dosis letal media (LD50) en la que se utilizan animales para efectuar pruebas de toxicidad aguda. A estos se les administra de uno en uno una dosis de un fármaco o sustancia tóxica. Si un animal sobrevive, se aumenta la dosis para el siguiente; si muere, se reduce la dosis para determinar el nivel de toxicidad."@es ;
  dc:source "Based upon Bruce R. D. (1985). An up-and-down procedure for acute toxicity testing. Fundamental and applied toxicology : official journal of the Society of Toxicology, 5(1), 151–157. " .

nalt:28890315 skos:definition nalt:28890315_def .