@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:291499_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Serina treonina cinasa que controla una amplia gama de procesos celulares relativos al crecimiento. La proteína es denominada como la diana de rapamicina debido al descubrimiento de que el sirolimus, conocido comúnmente como rapamicina, forma un complejo inhibidor con la proteína 1A de unión a tracolimus, que bloquea la acción de su actividad enzimática."@es, "A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of rapamycin due to the discovery that sirolimus (commonly known as rapamycin) forms an inhibitory complex with tacrolimus binding protein 1A that blocks the action of its enzymatic activity."@en ;
  dc:source "Medical Subject Headings 2017" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:291499
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  dc:created "2017-02-06"^^xsd:date ;
  dc:modified "2017-11-10"^^xsd:date ;
  skos:altLabel "target of rapamycin kinases"@en, "TOR (target of rapamycin) kinases"@en, "rapamycin target proteins"@en ;
  skos:broader nalt:217155 ;
  skos:definition nalt:291499_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "proteínas de la diana de rapamicina"@es, "target of rapamycin proteins"@en ;
  skos:related nalt:291508, nalt:291300, nalt:146229 ;
  ns0:marc001 "84113" .

nalt:291508
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "target of rapamycin signaling pathways"@en, "vías de señalización de la diana de rapamicina"@es ;
  skos:related nalt:291499 .

nalt:291300
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "rapamicina"@es, "rapamycin"@en ;
  skos:related nalt:291499 .

nalt:217155
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:291499 ;
  skos:prefLabel "péptidos y proteínas de señalización intracelular"@es, "intracellular signaling peptides and proteins"@en .

nalt:146229
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "protein-serine-threonine kinases"@en, "proteína-serina-treonina quinasas"@es ;
  skos:related nalt:291499 .