@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .

<https://lod.nal.usda.gov/naltv#Definition>
  a owl:Class ;
  rdfs:label "Concept definition"@en .

nalt:341360_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "A derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethylglutaryl CoA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL receptors, it increases breakdown of LDL cholesterol."@en, "Derivado de la lovastatina y un potente inhibidor competitivo de la 3-hidroxi-3-metilglutaril-coenzima-A reductasa (hidroximetilglutaril CoA reductasas), que constituye la enzima limitante en la biosíntesis del colesterol. Además, puede intervenir en la producción de hormonas esteroides. Debido a la inducción de receptores de LDL hepático, incrementa la descomposición del colesterol LDL."@es ;
  dc:source "Medical Subject Headings" .

nalt:341360 skos:definition nalt:341360_def .