@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:34181_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a mutation or a block of DNA replication. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (pyrimidine dimers) or interstrand crosslinking. Damage can often be repaired. If the damage is extensive, it can induce apoptosis."@en, "Daño producido por medicamentos o radiación al ADN que producen anormalidades en su conformación de doble hélice."@es ;
  dc:source "Medical Subject Headings 2012" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Topic>
  a owl:Class ;
  rdfs:label "Topic"@en .

nalt:34181
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Topic> ;
  dc:created "2006-01-19"^^xsd:date ;
  dc:modified "2018-10-11"^^xsd:date ;
  skos:altLabel "DNA injury"@en ;
  skos:broader nalt:7772 ;
  skos:definition nalt:34181_def ;
  skos:exactMatch <http://id.loc.gov/authorities/subjects/sh88006186>, <http://id.agrisemantics.org/gacs/C7740> ;
  skos:inScheme <https://lod.nal.usda.gov/nalt>, <https://lod.nal.usda.gov/nalt-core> ;
  skos:prefLabel "DNA damage"@en, "daño al ADN"@es ;
  skos:related nalt:262750, nalt:291475, nalt:11246, nalt:15974, nalt:7777, nalt:34182, nalt:122403 ;
  ns0:marc001 "12385" .

nalt:262750
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "etoposide"@en, "etopósido"@es ;
  skos:related nalt:34181 .

nalt:291475
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "ensayo cometa"@es, "comet assay"@en ;
  skos:related nalt:34181 .

nalt:11246
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "DNA fragmentation"@en, "fragmentación de ADN"@es ;
  skos:related nalt:34181 .

nalt:15974
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "reparación de ADN"@es, "DNA repair"@en ;
  skos:related nalt:34181 .

nalt:122403
  a ns0:Chemical, skos:Concept ;
  skos:prefLabel "mutágenos"@es, "mutagens"@en ;
  skos:related nalt:34181 .

nalt:34182
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "genotoxicidad"@es, "genotoxicity"@en ;
  skos:related nalt:34181 .

nalt:7777
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "mutación"@es, "mutation"@en ;
  skos:related nalt:34181 .

nalt:7772
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34181 ;
  skos:prefLabel "genética molecular"@es, "molecular genetics"@en .