@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix agrovoc: <http://aims.fao.org/aos/agrovoc/> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:34640_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Dynamic and kinetic mechanisms of exogenous chemical and drug absorption; biological transport; tissue distribution; biotransformation; elimination; and toxicology as a function of dosage, and rate of metabolism. It includes toxicokinetics, the pharmacokinetic mechanism of the toxic effects of a substance. ADME and ADMET are short- hand abbreviations for absorption, distribution, metabolism, elimination and toxicology."@en, "Mecanismo dinámico y cinético de sustancias exógenas y absorción, adsorción, biotransformación, distribución, liberación, transporte, ingestión y eliminación de medicamentos como función de dosificación, extensión y tasa de procesos metabólicos. Incluye a la toxicocinética, los mecanismos farmacocinéticos de los efectos tóxicos de una sustancia."@es ;
  dc:source "Medical Subject Headings 2012" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Topic>
  a owl:Class ;
  rdfs:label "Topic"@en .

nalt:34640
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Topic> ;
  dc:created "2006-01-19"^^xsd:date ;
  dc:modified "2020-01-17"^^xsd:date ;
  skos:altLabel "drug metabolism"@en, "drug biotransformation"@en, "drug kinetics"@en, "toxicokinetics"@en, "drug absorption"@en ;
  skos:broader nalt:8301, nalt:35791, nalt:24572 ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh85039737> ;
  skos:definition nalt:34640_def ;
  skos:exactMatch <http://id.cabi.org/cabt/88429>, <http://id.loc.gov/authorities/subjects/sh00006940>, agrovoc:c_13280, <http://id.loc.gov/authorities/subjects/sh85100597>, <http://id.agrisemantics.org/gacs/C3177> ;
  skos:inScheme <https://lod.nal.usda.gov/nalt>, <https://lod.nal.usda.gov/nalt-core>, <https://lod.nal.usda.gov/nalt-awic> ;
  skos:narrower nalt:192533 ;
  skos:prefLabel "pharmacokinetics"@en, "farmacocinética"@es ;
  skos:related nalt:313430, nalt:34639, nalt:238256, nalt:34993, nalt:88549 ;
  ns0:marc001 "28036" .

nalt:313430
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "diseño de fármacos"@es, "drug design"@en ;
  skos:related nalt:34640 .

nalt:192533
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:34640 ;
  skos:prefLabel "biological half-life"@en, "semivida biológica"@es .

nalt:34639
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "excreción de medicamentos"@es, "drug excretion"@en ;
  skos:related nalt:34640 .

nalt:238256
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "farmacometría"@es, "pharmacometrics"@en ;
  skos:related nalt:34640 .

nalt:34993
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "cinética"@es, "kinetics"@en ;
  skos:related nalt:34640 .

nalt:24572
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34640 ;
  skos:prefLabel "farmacología"@es, "pharmacology"@en .

nalt:88549
  a ns0:Topic, skos:Concept ;
  skos:prefLabel "farmacodinámica"@es, "pharmacodynamics"@en ;
  skos:related nalt:34640 .

nalt:35791
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34640 ;
  skos:prefLabel "toxicología"@es, "toxicology"@en .

nalt:8301
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34640 ;
  skos:prefLabel "metabolismo"@es, "metabolism"@en .