@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

<https://lod.nal.usda.gov/naltv#marc001> rdfs:label "Field 001 in MARC Authority Format"@en .
nalt:3814_def
  a <https://lod.nal.usda.gov/naltv#Definition> ;
  rdf:value "Compuesto que consta de dos péptidos cíclicos unidos a una fenoxazina derivada de Streptomyces parvullus. Se une al ADN e inhibe la síntesis de ARN (transcripción), con el alargamiento de la cadena más sensible que al inicio, terminación o liberación, lo que da como resultado la producción deteriorada de ARNm y la disminución de la síntesis de proteínas después de la terapia con dactinomicina."@es, "A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from Streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy."@en ;
  dc:source "Medical Subject Headings 2011" .

<https://lod.nal.usda.gov/nalt>
  a skos:ConceptScheme ;
  rdfs:label "NALT Full"@en .

<https://lod.nal.usda.gov/naltv#Chemical>
  a owl:Class ;
  rdfs:label "Chemical"@en .

nalt:3814
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  dc:created "2006-01-19"^^xsd:date ;
  dc:modified "2017-11-17"^^xsd:date ;
  skos:altLabel "dactinomycin"@en ;
  skos:broader nalt:10206, nalt:31026, nalt:3817, nalt:3816 ;
  skos:definition nalt:3814_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "actinomicina D"@es, "actinomycin D"@en ;
  ns0:marc001 "834" .

nalt:10206
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:3814 ;
  skos:prefLabel "antibióticos péptidos"@es, "peptide antibiotics"@en .

nalt:31026
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:3814 ;
  skos:prefLabel "cyclic peptides"@en, "péptidos cíclicos"@es .

nalt:3817
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:3814 ;
  skos:prefLabel "compuestos heterocíclicos"@es, "heterocyclic compounds"@en .

nalt:3816
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:3814 ;
  skos:prefLabel "agentes antineoplásicos"@es, "antineoplastic agents"@en .